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Derrius Guice saw action in 12 games, playing behind Leonard Fournette as a true freshman (2015). Finished with 436 yards on 51 carries (8.5 avg.), and scored 3 rushing touchdowns. With Fournette injured in 2016; Guice got his opportunity and started 6 games. Took advantage of his opportunity and led the SEC in rushing and rushing touchdowns. Finished his sophomore campaign with 1,387 yards on 183 carries (7.6 avg.), with 15 rushing touchdowns and a receiving touchdown.
11/24/2016 – Derrius Guice breaks LSU all-time single game rushing record with 285 yards in road win (54-39) over Texas A&M.